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Nervousness / Anxiety
GABA & Glutamate Balance
TrancorTM is formulated to support a sense of tranquility in those who may feel worried or nervous by beneficially modulating the balance between the calming influence of GABA and the excitatory effects of glutamate. Designed
to act centrally, within the brain, this advanced formula features the amino acids NAC and taurine-which research suggests may be able to cross the bloodbrain barrier-along with concentrated green tea catechins, vitamin B6, and magnesium malate for targeted neurological support.
Patient benefits:
- Supports a sense of tranquility by modulating the balance between glutamate and GABA with NAC, green
tea catechins, and vitamin B6
- Helps protect nerve cells from the excitotoxic effects of excess glutamate and other pro-oxidant influences with taurine and EGCG
- Supports relaxation and a sense of calm with magnesium and vitamin B6
Suggested Nutritional Supplementation
- TrancorTM - Four capsules daily
Trancor is formulated to support a sense of tranquility in those who may feel worried or nervous by beneficially modulating the balance between the calming influence of GABA and the excitatory effects of glutamate.
- Serenagen® - 2-6 tablets daily
Serenagen is a classic, comprehensive herbal stress management formula targeting individuals who are
"stressed and wired".
Recommended uses:
- Nervousness
- Support for tranquility
CAUTION: Do not use if pregnant or nursing. Use with caution if patient has congestive heart failure or kidney disease, or is taking medication - including anticoagulants. Maintain adequate fluid intake while taking this product.
Refrences:
1. Farr SA, Poon HF, Dogrukol-Ak D, et al. The antioxidants alphalipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. J Neurochem 2003;84(5):1173-83.
2. Neuwelt EA, Pagel MA, Hasler BP, et al. Therapeutic efficacy of aortic administration of N-acetylcysteine as a chemoprotectant against bone marrow toxicity after intracarotid administration of alkylators, with or without glutathione depletion in a rat model. Cancer Res 2001;61:7868-74.
3. Adachi N, Tomonaga S, Tachibana T, et al. (-)-Epigallocatechin gallate attenuates acute stress responses through GABAergic system in the brain. Eur J Pharmacol 2005;531:171-75.
4. Vignes M, Maurice T, Lante F, et al. Anxiolytic properties of green tea polyphenol (-)-epigallocatechin gallate (EGCG). Brain Res 2006 Jul 19; [Epub].
5. Paula-Lima AC, De Felice FG, Brito-Moreira J, et al. Activation of GABA(A) receptors by taurine and muscimol blocks the neurotoxicity of beta- amyloid in rat hippocampal and cortical neurons. Neuropharmacol 2005;49:1140-48.
6. Stummer W, Betz AL, Shakui P, et al. Blood-brain barrier taurine transport during osmotic stress and in focal cerebral ischemia. J Cereb Blood Flow Metab 1995;15(5):852-59.
7. Oja SS, Saransaari P. Taurine as osmoregulator and neuromodulator in the brain. Metab Brain Dis 1996;11(2):153-64.
8. Poleszak E, Szewczyk B, Kedzierska E, et al. Antidepressant- and anxiolytic-like activity of magnesium in mice. Pharmacol Biochem Behav 2004;78(1):7-12.
9. De Souza MC, Walker AF, Robinson PA, et al. A synergistic effect of a daily supplement for 1 month of 200 mg magnesium plus 50 mg vitamin B6 for the relief of anxiety-related premenstrual symptoms: a randomized, double-blind, crossover study. J Womens Health Gend Based Med 2000;9(2):131-39.
10. McCarty MF. High-dose pyridoxine as an ‘anti-stress' strategy. Med Hypotheses 2000;54(5):803-07.