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Supplements and Vitamins
Folic Acid, Vitamin B6, Vitamin B12, Betaine
Many studies indicate that patients with elevated levels of the amino acid homocysteine are roughly 1.7 times more likely to develop coronary artery disease and 2.5 times more likely to suffer from a stroke than those with normal levels. Homocysteine levels are strongly influenced by dietary factors, particularly vitamin B9 (folic acid), vitamin B6, vitamin B12, and betaine. These substances help break down homocysteine in the body. Some studies have even shown that healthy individuals who consume higher amounts of folic acid and vitamin B6 are less likely to develop atherosclerosis than those who consume lower amounts of these substances.
Omega-3 Fatty Acids
There is strong evidence that omega-3 fatty acids (namely EPA and DHA) found in fish oil can help prevent and treat atherosclerosis by inhibiting the development of plaques and blood clots. In one study of 223 patients with coronary artery disease, those who received fish oil supplements daily for 2 years demonstrated a significant improvement in symptoms compared to those who did not receive the supplements. A second study of heart attack survivors found that daily supplementation with omega-3 fatty acids dramatically reduced the rate of death, subsequent heart attacks, and stroke.
L-Carnitine
Studies suggest that patients who take L-carnitine supplementation soon after suffering a heart attack may be less likely to suffer a subsequent heart attack, die of heart disease, and experience chest pain and abnormal heart rhythms. In addition, people with coronary artery disease who use L-carnitine along with standard medication may be able to sustain physical activity for longer periods of time.
Antioxidants
Evidence suggests that antioxidants may play a role in the prevention of atherosclerosis. Antioxidants are believed
to prevent fatty buildup in the arteries by suppressing the oxidation of LDL ("bad") cholesterol. They may also reduce the likelihood of blood clot formation and may help relax blood vessels thereby improving blood flow.
Vitamin E
Population-based studies suggest that vitamin E supplements may help prevent the development and progression
of heart disease.
Selenium
Low blood levels of this antioxidant may worsen atherosclerosis. Cigarette smoking and alcohol ingestion are believed to contribute to selenium deficiency. It is not known, however, whether selenium supplementation has any influence on the development or progression of atherosclerosis.
Coenzyme Q10 (CoQ10)
Researchers believe that CoQ10 inhibits blood clot formation and boosts levels of antioxidants. One study found that people who received daily CoQ10 supplements within 3 days of a heart attack were significantly less likely to experience subsequent heart attacks and chest pain and were also less likely to die of the condition than those
who did not receive the supplements.
Flavonoids
Test tube, animal, and some population-based studies suggest that the flavonoids quercetin, resveratrol, and catechins (all found in high concentration in red wine) may help reduce the risk of atherosclerosis. By acting as antioxidants, there nutrients appear to protect against the damage caused by LDL cholesterol.
Vitamin D
Low levels of vitamin D may increase the risk of calcium build-up in the arteries, a significant component of
atherosclerotic plaque. Atherosclerotic plaque build up in blood vessels can lead to a heart attack or stroke.
Melatonin
Low levels of melatonin in the blood have been associated with heart disease, but it is not clear, whether melatonin levels are low in response to having heart disease or if low levels of melatonin predispose people to developing this condition. In addition, several studies in rats suggest that melatonin may protect the hearts of these animals from the damaging effects of ischemia.
Herbs
- Hawthorn (Crataegus monogyna): Used traditionally as a remedy for cardiovascular diseases. Animal
and laboratory studies demonstrate that this herb has antioxidant properties that help protect against the
formation of plaques and may help control high cholesterol and high blood pressure.
- Garlic (Allium sativum): Clinical trials have shown that fresh garlic and garlic supplements may lower
cholesterol levels, prevent blood clots, and destroy plaque.
- Green Tea (Camellia sinensis): Population studies indicate that the antioxidant properties of green tea may
prevent atherosclerosis, particularly coronary artery disease.
- Gugulipid (Commiphora mukul): Used in Ayurvedic medicine to treat high cholesterol levels. Certain ingredients in this herbal remedy may have antioxidant properties and may therefore convey health benefits similar to hawthorn, garlic, and green tea.
- Pseudo ginseng root/notoginseng root (Panax notoginseng): Used in Traditional Chinese Medicine to treat chest pain and coronary artery disease. Laboratory studies suggest this herb may help prevent blood clots and protect against the formation of plaques.
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