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Ankylosis Spondylitis
Ankylosis Spondylitis is defined as a chronic and generally progressive inflammatory arthritic disease affecting the spinal joints and adjacent connective tissues. Also called "Marie Strumpell Disease." This appears to be a disease mainly of young men aged 10-30 years old. It seems to have a genetic component, as it is seen in male relatives and especially in patients with histocompatibility complex HLA-B27 (who have a 300 times greater risk of developing AS, particularly in white men). The etiology is unknown. It is seen throughout the world.
Conventional treatment does not stop the progression of the disease. Stretching exercises and careful adherence to correct posturing are absolutely required to maintain as much mobility as possible over time. Occasionally surgery is used to replace a badly affected joint or to straighten the spine.